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Depurinating estrogen–DNA adducts in the etiology and prevention of breast and other human cancers
Experiments on estrogen metabolism, formation of DNA adducts, mutagenicity, cell transformation and carcinogenicity have led to and supported the hypothesis that the reaction of specific estrogen metabolites, mostly the electrophilic catechol estrogen-3,4-quinones, with DNA can generate the critical...
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| 發表在: | Future Oncol |
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| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4422115/ https://ncbi.nlm.nih.gov/pubmed/20021210 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fon.09.137 |
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