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The etiology and prevention of breast cancer

Metabolism of estrogens via the catechol estrogen pathway is characterized by a balanced set of activating and protective enzymes (homeostasis). Disruption of homeostasis, with excessive production of catechol estrogen quinones, can lead to reaction of these quinones with DNA to form depurinating es...

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Bibliografiske detaljer
Udgivet i:Drug Discov Today Dis Mech
Main Authors: Cavalieri, Ercole L., Rogan, Eleanor G.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4522944/
https://ncbi.nlm.nih.gov/pubmed/26246832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ddmec.2013.02.001
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