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Etiology and prevention of prevalent types of cancer

Endogenous estrogens become carcinogens when excessive catechol estrogen quinone metabolites are formed. Specifically, the catechol estrogen-3,4-quinones can react with DNA to produce a large amount of specific depurinating estrogen-DNA adducts, formed at the N-3 of Ade and N-7 of Gua. Loss of these...

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Bibliografiske detaljer
Udgivet i:J Rare Dis Res Treat
Main Authors: Cavalieri, Ercole L., Rogan, Eleanor G.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6404759/
https://ncbi.nlm.nih.gov/pubmed/30854528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.29245/2572-9411/2017/3.1093
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