A carregar...
N-Acetylcysteine blocks formation of cancer-initiating estrogen-DNA adducts in cells
Catechol estrogens, especially 4-hydroxylated metabolites of 17β-estradiol (E(2)), are responsible for estrogen-induced carcinogenesis. 4-Hydroxyestradiol (4-OHE(2)), a major metabolite of E(2) formed preferentially by cytochrome P-450 1B1, is oxidized to E(2)-3,4-quinone, which can react with DNA t...
Na minha lista:
| Main Authors: | , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2900421/ https://ncbi.nlm.nih.gov/pubmed/20472053 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2010.04.028 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|