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Constraint and divergence of global gene expression in the mammalian embryo

The effects of genetic variation on gene regulation in the developing mammalian embryo remain largely unexplored. To globally quantify these effects, we crossed two divergent mouse strains and asked how genotype of the mother or of the embryo drives gene expression phenotype genomewide. Embryonic ex...

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Détails bibliographiques
Publié dans:eLife
Auteurs principaux: Spies, Noah, Smith, Cheryl L, Rodriguez, Jesse M, Baker, Julie C, Batzoglou, Serafim, Sidow, Arend
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4417935/
https://ncbi.nlm.nih.gov/pubmed/25871848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.05538
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