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Distribution and intensity of constraint in mammalian genomic sequence
Comparisons of orthologous genomic DNA sequences can be used to characterize regions that have been subject to purifying selection and are enriched for functional elements. We here present the results of such an analysis on an alignment of sequences from 29 mammalian species. The alignment captures...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1172034/ https://ncbi.nlm.nih.gov/pubmed/15965027 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.3577405 |
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