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Helix 8 of the Ligand Binding Domain of the Glucocorticoid Receptor (GR) is Essential for Ligand Binding

Membrane association of estrogen receptors (ER) depends on cysteine palmitoylation and two leucines in the ligand binding domain (LBD), conserved in most steroid receptors. The role of this region, corresponding to helix 8 of the glucocorticoid receptor (GR) LBD, on membrane association of GR was st...

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Dettagli Bibliografici
Pubblicato in:Mol Cell Endocrinol
Autori principali: Deng, Qiong, Waxse, Bennett, Riquelme, Denise, Zhang, Jiabao, Aguilera, Greti
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4417367/
https://ncbi.nlm.nih.gov/pubmed/25676569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2015.01.044
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