Helix 8 of the Ligand Binding Domain of the Glucocorticoid Receptor (GR) is Essential for Ligand Binding

Membrane association of estrogen receptors (ER) depends on cysteine palmitoylation and two leucines in the ligand binding domain (LBD), conserved in most steroid receptors. The role of this region, corresponding to helix 8 of the glucocorticoid receptor (GR) LBD, on membrane association of GR was st...

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Publicado en:Mol Cell Endocrinol
Autores principales: Deng, Qiong, Waxse, Bennett, Riquelme, Denise, Zhang, Jiabao, Aguilera, Greti
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4417367/
https://ncbi.nlm.nih.gov/pubmed/25676569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2015.01.044
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