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Helix 8 of the Ligand Binding Domain of the Glucocorticoid Receptor (GR) is Essential for Ligand Binding

Membrane association of estrogen receptors (ER) depends on cysteine palmitoylation and two leucines in the ligand binding domain (LBD), conserved in most steroid receptors. The role of this region, corresponding to helix 8 of the glucocorticoid receptor (GR) LBD, on membrane association of GR was st...

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Detalhes bibliográficos
Publicado no:Mol Cell Endocrinol
Main Authors: Deng, Qiong, Waxse, Bennett, Riquelme, Denise, Zhang, Jiabao, Aguilera, Greti
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4417367/
https://ncbi.nlm.nih.gov/pubmed/25676569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2015.01.044
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