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The epigenetic landscape of lineage choice: lessons from the heritability of Cd4 and Cd8 expression

Developing αβ T cells choose between the helper and cytotoxic lineages, depending upon the specificity of their T cell receptors for MHC molecules. The expression of the CD4 co-receptor on helper cells and the CD8 co-receptor on cytotoxic cells is intimately linked to this decision, and their regula...

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Detalhes bibliográficos
Publicado no:Curr Top Microbiol Immunol
Main Authors: Gialitakis, Manolis, Sellars, MacLean, Littman, Dan R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4417357/
https://ncbi.nlm.nih.gov/pubmed/21989924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/82_2011_175
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