Heritable Gene Regulation in the CD4:CD8 T Cell Lineage Choice

The adaptive immune system is dependent on functionally distinct lineages of T cell antigen receptor αβ-expressing T cells that differentiate from a common progenitor in the thymus. CD4(+)CD8(+) progenitor thymocytes undergo selection following interaction with MHC class I and class II molecules bea...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Issuree, Priya D. A., Ng, Charles P., Littman, Dan R.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2017
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5360760/
https://ncbi.nlm.nih.gov/pubmed/28382035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00291
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