Active displacement of RecA filaments by UvrD translocase activity

The UvrD helicase has been implicated in the disassembly of RecA nucleoprotein filaments in vivo and in vitro. We demonstrate that UvrD utilizes an active mechanism to remove RecA from the DNA. Efficient RecA removal depends on the availability of DNA binding sites for UvrD and/or the accessibility...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nucleic Acids Res
Päätekijät: Petrova, Vessela, Chen, Stefanie H., Molzberger, Eileen T., Tomko, Eric, Chitteni-Pattu, Sindhu, Jia, Haifeng, Ordabayev, Yerdos, Lohman, Timothy M., Cox, Michael M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2015
Aiheet:
Nucleic Acid Enzymes
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4417151/
https://ncbi.nlm.nih.gov/pubmed/25824953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv186
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