Active displacement of RecA filaments by UvrD translocase activity

The UvrD helicase has been implicated in the disassembly of RecA nucleoprotein filaments in vivo and in vitro. We demonstrate that UvrD utilizes an active mechanism to remove RecA from the DNA. Efficient RecA removal depends on the availability of DNA binding sites for UvrD and/or the accessibility...

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Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Main Authors: Petrova, Vessela, Chen, Stefanie H., Molzberger, Eileen T., Tomko, Eric, Chitteni-Pattu, Sindhu, Jia, Haifeng, Ordabayev, Yerdos, Lohman, Timothy M., Cox, Michael M.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2015
Teme:
Nucleic Acid Enzymes
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4417151/
https://ncbi.nlm.nih.gov/pubmed/25824953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv186
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