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Active displacement of RecA filaments by UvrD translocase activity
The UvrD helicase has been implicated in the disassembly of RecA nucleoprotein filaments in vivo and in vitro. We demonstrate that UvrD utilizes an active mechanism to remove RecA from the DNA. Efficient RecA removal depends on the availability of DNA binding sites for UvrD and/or the accessibility...
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| Izdano u: | Nucleic Acids Res |
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| Glavni autori: | , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2015
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4417151/ https://ncbi.nlm.nih.gov/pubmed/25824953 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv186 |
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