Active displacement of RecA filaments by UvrD translocase activity

The UvrD helicase has been implicated in the disassembly of RecA nucleoprotein filaments in vivo and in vitro. We demonstrate that UvrD utilizes an active mechanism to remove RecA from the DNA. Efficient RecA removal depends on the availability of DNA binding sites for UvrD and/or the accessibility...

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Publicat a:Nucleic Acids Res
Autors principals: Petrova, Vessela, Chen, Stefanie H., Molzberger, Eileen T., Tomko, Eric, Chitteni-Pattu, Sindhu, Jia, Haifeng, Ordabayev, Yerdos, Lohman, Timothy M., Cox, Michael M.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2015
Matèries:
Nucleic Acid Enzymes
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4417151/
https://ncbi.nlm.nih.gov/pubmed/25824953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv186
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