Intact Glycosaminoglycans from intervertebral disc-derived notochordal cell conditioned media inhibits neurite growth while maintaining neuronal cell viability

BACKGROUND CONTEXT: Painful human intervertebral discs (IVDs) exhibit nerve growth deep into the IVD. Current treatments for discogenic back pain do not address the underlying mechanisms propagating pain and are often highly invasive or only offer temporary symptom relief. The notochord produces fac...

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Detaylı Bibliyografya
Yayımlandı:Spine J
Asıl Yazarlar: Purmessur, Devina, Cornejo, Marisa C, Cho, Samuel K, Roughley, Peter J, Linhardt, Robert J, Hecht, Andrew C, Iatridis, James C
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416992/
https://ncbi.nlm.nih.gov/pubmed/25661435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.spinee.2015.02.003
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