Articular cartilage and changes in arthritis: Noncollagenous proteins and proteoglycans in the extracellular matrix of cartilage

Por Roughley, Peter J
Publicado em 2001

The role of aggrecan in normal and osteoarthritic cartilage

Por Roughley, Peter J, Mort, John S
Publicado no J Exp Orthop (2014)

Variations in aggrecan structure modulate its susceptibility to aggrecanases.

Por Roughley, Peter J, Barnett, James, Zuo, Fengrong, Mort, John S
Publicado em 2003

MMPs are less efficient than ADAMTS5 in cleaving aggrecan core protein

Por Durigova, Michaela, Nagase, Hideaki, Mort, John S., Roughley, Peter J.
Publicado em 2010

The mechanism of aggrecan release from cartilage differs with tissue origin and the agent used to stimulate catabolism.

Por Sztrolovics, Robert, White, Robert J, Roughley, Peter J, Mort, John S
Publicado em 2002

Hyaluronate degradation as an alternative mechanism for proteoglycan release from cartilage during interleukin-1beta-stimulated catabolism.

Por Sztrolovics, Robert, Recklies, Anneliese D, Roughley, Peter J, Mort, John S
Publicado em 2002

Aggrecan heterogeneity in articular cartilage from patients with osteoarthritis

Por Mort, John S., Geng, Yeqing, Fisher, William D., Roughley, Peter J.
Publicado no BMC Musculoskelet Disord (2016)

Absence of the dermatan sulfate chain of decorin does not affect mouse development

Por Moffatt, Pierre, Geng, Yeqing, Lamplugh, Lisa, Nanci, Antonio, Roughley, Peter J.
Publicado no J Negat Results Biomed (2017)

Region-dependent aggrecan degradation patterns in the rat intervertebral disc are affected by mechanical loading in vivo

Por Iatridis, James C., Godburn, Karolyn, Wuertz, Karin, Alini, Mauro, Roughley, Peter J.
Publicado em 2011

Effects of Mechanical Loading on Intervertebral Disc Metabolism In Vivo

Por Iatridis, James C., MacLean, Jeffrey J., Roughley, Peter J., Alini, Mauro
Publicado em 2006

Glypican and Biglycan in the Nuclei of Neurons and Glioma Cells: Presence of Functional Nuclear Localization Signals and Dynamic Changes in Glypican During the Cell Cycle

Por Liang, Yu, Häring, Monika, Roughley, Peter J., Margolis, Renée K., Margolis, Richard U.
Publicado em 1997

Intervertebral disc changes with angulation, compression and reduced mobility simulating altered mechanical environment in scoliosis

Por Stokes, Ian A. F., McBride, Carole, Aronsson, David D., Roughley, Peter J.
Publicado em 2011

METABOLIC EFFECTS OF ANGULATION, COMPRESSION AND REDUCED MOBILITY ON ANNULUS FIBROSIS IN A MODEL OF ALTERED MECHANICAL ENVIRONMENT IN SCOLIOSIS

Por Stokes, Ian A.F., McBride, Carole, Aronsson, David D., Roughley, Peter J.
Publicado em 2013

Cells from the skin of patients with systemic sclerosis secrete chitinase 3-like protein 1

Por Ho, Yuen Yee, Baron, Murray, Recklies, Anneliese D., Roughley, Peter J., Mort, John S.
Publicado no BBA Clin (2014)

The structure and degradation of aggrecan in human intervertebral disc

Por Roughley, Peter J., Melching, Lee I., Heathfield, Terrence F., Pearce, Richard H., Mort, John S.
Publicado em 2006

In Vivo Intervertebral Disc Remodeling: Kinetics of mRNA Expression in Response to a Single Loading Event

Por MacLean, Jeffrey J., Roughley, Peter J., Monsey, Robert D., Alini, Mauro, Iatridis, James C.
Publicado em 2008

The effect of Link N on differentiation of human bone marrow-derived mesenchymal stem cells

Por Antoniou, John, Wang, Hong Tian, Alaseem, Abdulrahman M, Haglund, Lisbet, Roughley, Peter J, Mwale, Fackson
Publicado em 2012

Analysis of Intimal Proteoglycans in Atherosclerosis-prone and Atherosclerosis-resistant Human Arteries by Mass Spectrometry

Por Talusan, Paul, Bedri, Shahinaz, Yang, Suping, Kattapuram, Taj, Silva, Nilsa, Roughley, Peter J., Stone, James R.
Publicado em 2005

TNFα Transport Induced by Dynamic Loading Alters Biomechanics of Intact Intervertebral Discs

Por Walter, Benjamin A., Likhitpanichkul, Morakot, Illien-Junger, Svenja, Roughley, Peter J., Hecht, Andrew C., Iatridis, James C.
Publicado no PLoS One (2015)

Biglycan and fibromodulin fragmentation correlates with temporal and spatial annular remodelling in experimentally injured ovine intervertebral discs

Por Melrose, James, Smith, Susan M., Fuller, Emily S., Young, Allan A., Roughley, Peter J., Dart, Andrew, Little, Christopher B.
Publicado em 2007