Arterial thrombosis is accelerated in mice deficient in histidine-rich glycoprotein

Factor (F) XII, a key component of the contact system, triggers clotting via the intrinsic pathway, and is implicated in propagating thrombosis. Although nucleic acids are potent activators, it is unclear how the contact system is regulated to prevent uncontrolled clotting. Previously, we showed tha...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Vu, Trang T., Zhou, Ji, Leslie, Beverly A., Stafford, Alan R., Fredenburgh, James C., Ni, Ran, Qiao, Shengjun, Vaezzadeh, Nima, Jahnen-Dechent, Willi, Monia, Brett P., Gross, Peter L., Weitz, Jeffrey I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2015
Assuntos:
Thrombosis and Hemostasis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416941/
https://ncbi.nlm.nih.gov/pubmed/25691157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-11-611319
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