Arterial thrombosis is accelerated in mice deficient in histidine-rich glycoprotein

Factor (F) XII, a key component of the contact system, triggers clotting via the intrinsic pathway, and is implicated in propagating thrombosis. Although nucleic acids are potent activators, it is unclear how the contact system is regulated to prevent uncontrolled clotting. Previously, we showed tha...

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Bibliografiske detaljer
Udgivet i:Blood
Main Authors: Vu, Trang T., Zhou, Ji, Leslie, Beverly A., Stafford, Alan R., Fredenburgh, James C., Ni, Ran, Qiao, Shengjun, Vaezzadeh, Nima, Jahnen-Dechent, Willi, Monia, Brett P., Gross, Peter L., Weitz, Jeffrey I.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2015
Fag:
Thrombosis and Hemostasis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416941/
https://ncbi.nlm.nih.gov/pubmed/25691157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-11-611319
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