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Kinetic Mechanism of Protein N-terminal Methyltransferase 1

The protein N-terminal methyltransferase 1 (NTMT1) catalyzes the transfer of the methyl group from the S-adenosyl-l-methionine to the protein α-amine, resulting in formation of S-adenosyl-l-homocysteine and α-N-methylated proteins. NTMT1 is an interesting potential anticancer target because it is ov...

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Vydáno v:J Biol Chem
Hlavní autoři: Richardson, Stacie L., Mao, Yunfei, Zhang, Gang, Hanjra, Pahul, Peterson, Darrell L., Huang, Rong
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416863/
https://ncbi.nlm.nih.gov/pubmed/25771539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.626846
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