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Design and Synthesis of Novel Arctigenin Analogues for the Amelioration of Metabolic Disorders
[Image: see text] Analogues of the natural product (−)-arctigenin, an activator of adenosine monophosphate activated protein kinase, were prepared in order to evaluate their effects on 2-deoxyglucose uptake in L6 myotubes and possible use in ameliorating metabolic disorders. Racemic arctigenin 2a wa...
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| Publicado en: | ACS Med Chem Lett |
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| Autores principales: | , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Chemical
Society
2015
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| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4416425/ https://ncbi.nlm.nih.gov/pubmed/25941553 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.5b00007 |
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