Design and synthesis of novel oridonin analogues as potent anticancer agents

To identify anticancer agents with higher potency and lower toxicity, a series of oridonin derivatives with substituted benzene moieties at the C17 position were designed, synthesised, and evaluated for their antiproliferative properties. Most of the derivatives exhibited antiproliferative effects a...

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Bibliografiske detaljer
Udgivet i:J Enzyme Inhib Med Chem
Main Authors: Shen, Qing-Kun, Chen, Zheng-Ai, Zhang, Hong-Jian, Li, Jia-Li, Liu, Chuan-Feng, Gong, Guo-Hua, Quan, Zhe-Shan
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2018
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054517/
https://ncbi.nlm.nih.gov/pubmed/29303372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2017.1419219
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