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Design, synthesis and evaluation of PD176252 analogues for ameliorating cisplatin-induced nephrotoxicity
Cisplatin is a clinical chemotherapy drug for cancers; however, its remarkably high kidney toxicity and other toxicities pose a danger to patients. As the small molecule inhibitor of GRPR, PD176252 can inhibit the growth and proliferation of various cancer cells, but the characteristics of high toxi...
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| Publicado no: | Medchemcomm |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Royal Society of Chemistry
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6533884/ https://ncbi.nlm.nih.gov/pubmed/31191866 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8md00632f |
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