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Discovery of Imidazopyridine Derivatives as Highly Potent Respiratory Syncytial Virus Fusion Inhibitors

[Image: see text] A series of imidazolepyridine derivatives were designed and synthesized according to the established docking studies. The imidazopyridine derivatives were found to have good potency and physical-chemical properties. Several highly potent compounds such as 8ji, 8jl, and 8jm were ide...

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Publicado en:ACS Med Chem Lett
Autores principales: Feng, Song, Hong, Di, Wang, Baoxia, Zheng, Xiufang, Miao, Kun, Wang, Lisha, Yun, Hongying, Gao, Lu, Zhao, Shuhai, Shen, Hong C.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Chemical Society 2015
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416423/
https://ncbi.nlm.nih.gov/pubmed/25941547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.5b00008
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