Monoacylglycerol lipase inhibitor JZL184 reduces neuroinflammatory response in APdE9 mice and in adult mouse glial cells

BACKGROUND: Recently, the role of monoacylglycerol lipase (MAGL) as the principal regulator of simultaneous prostaglandin synthesis and endocannabinoid receptor activation in the CNS was demonstrated. To expand upon previously published research in the field, we observed the effect of the MAGL inhib...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Pihlaja, Rea, Takkinen, Jatta, Eskola, Olli, Vasara, Jenni, López-Picón, Francisco R, Haaparanta-Solin, Merja, Rinne, Juha O
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Short Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416350/
https://ncbi.nlm.nih.gov/pubmed/25927213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0305-9
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