Monoacylglycerol lipase inhibitor JZL184 reduces neuroinflammatory response in APdE9 mice and in adult mouse glial cells

BACKGROUND: Recently, the role of monoacylglycerol lipase (MAGL) as the principal regulator of simultaneous prostaglandin synthesis and endocannabinoid receptor activation in the CNS was demonstrated. To expand upon previously published research in the field, we observed the effect of the MAGL inhib...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Neuroinflammation
Egile Nagusiak: Pihlaja, Rea, Takkinen, Jatta, Eskola, Olli, Vasara, Jenni, López-Picón, Francisco R, Haaparanta-Solin, Merja, Rinne, Juha O
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2015
Gaiak:
Short Report
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416350/
https://ncbi.nlm.nih.gov/pubmed/25927213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0305-9
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