Potent Immune Responses in Rhesus Macaques Induced by Nonviral Delivery of a Self-amplifying RNA Vaccine Expressing HIV Type 1 Envelope With a Cationic Nanoemulsion

Self-amplifying messenger RNA (mRNA) of positive-strand RNA viruses are effective vectors for in situ expression of vaccine antigens and have potential as a new vaccine technology platform well suited for global health applications. The SAM vaccine platform is based on a synthetic, self-amplifying m...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Bogers, Willy M., Oostermeijer, Herman, Mooij, Petra, Koopman, Gerrit, Verschoor, Ernst J., Davis, David, Ulmer, Jeffrey B., Brito, Luis A., Cu, Yen, Banerjee, Kaustuv, Otten, Gillis R., Burke, Brian, Dey, Antu, Heeney, Jonathan L., Shen, Xiaoying, Tomaras, Georgia D., Labranche, Celia, Montefiori, David C., Liao, Hua-Xin, Haynes, Barton, Geall, Andrew J., Barnett, Susan W.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416123/
https://ncbi.nlm.nih.gov/pubmed/25234719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiu522
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