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Nonviral delivery of self-amplifying RNA vaccines
Despite more than two decades of research and development on nucleic acid vaccines, there is still no commercial product for human use. Taking advantage of the recent innovations in systemic delivery of short interfering RNA (siRNA) using lipid nanoparticles (LNPs), we developed a self-amplifying RN...
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| Main Authors: | , , , , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3437863/ https://ncbi.nlm.nih.gov/pubmed/22908294 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1209367109 |
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