Potent Immune Responses in Rhesus Macaques Induced by Nonviral Delivery of a Self-amplifying RNA Vaccine Expressing HIV Type 1 Envelope With a Cationic Nanoemulsion

Self-amplifying messenger RNA (mRNA) of positive-strand RNA viruses are effective vectors for in situ expression of vaccine antigens and have potential as a new vaccine technology platform well suited for global health applications. The SAM vaccine platform is based on a synthetic, self-amplifying m...

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Foilsithe in:J Infect Dis
Main Authors: Bogers, Willy M., Oostermeijer, Herman, Mooij, Petra, Koopman, Gerrit, Verschoor, Ernst J., Davis, David, Ulmer, Jeffrey B., Brito, Luis A., Cu, Yen, Banerjee, Kaustuv, Otten, Gillis R., Burke, Brian, Dey, Antu, Heeney, Jonathan L., Shen, Xiaoying, Tomaras, Georgia D., Labranche, Celia, Montefiori, David C., Liao, Hua-Xin, Haynes, Barton, Geall, Andrew J., Barnett, Susan W.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2015
Ábhair:
Major Articles and Brief Reports
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416123/
https://ncbi.nlm.nih.gov/pubmed/25234719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiu522
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