Production and Characterization of High-Titer Serum-Free Cell Culture Grown Hepatitis C Virus Particles of Genotype 1–6

Recently, cell culture systems producing hepatitis C virus particles (HCVcc) were developed. Establishment of serum-free culture conditions is expected to facilitate development of a whole-virus inactivated HCV vaccine. We describe generation of genotype 1–6 serum-free HCVcc (sf-HCVcc) from Huh7.5 h...

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Detalhes bibliográficos
Publicado no:Virology
Main Authors: Mathiesen, Christian K., Jensen, Tanja B., Prentoe, Jannick, Krarup, Henrik, Nicosia, Alfredo, Law, Mansun, Bukh, Jens, Gottwein, Judith M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4415741/
https://ncbi.nlm.nih.gov/pubmed/24928051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2014.03.021
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