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High density Huh7.5 cell hollow fiber bioreactor culture for high-yield production of hepatitis C virus and studies of antivirals

Chronic hepatitis C virus (HCV) infection poses a serious global public health burden. Despite the recent development of effective treatments there is a large unmet need for a prophylactic vaccine. Further, antiviral resistance might compromise treatment efficiency in the future. HCV cell culture sy...

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Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Pihl, Anne F., Offersgaard, Anna F., Mathiesen, Christian K., Prentoe, Jannick, Fahnøe, Ulrik, Krarup, Henrik, Bukh, Jens, Gottwein, Judith M.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6269495/
https://ncbi.nlm.nih.gov/pubmed/30504788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-35010-5
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