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Hypervariable region 1 shielding of hepatitis C virus is a main contributor to genotypic differences in neutralization sensitivity
There are 3-4 million new hepatitis C virus (HCV) infections yearly. The extensive inter-genotypic sequence diversity of envelope proteins E1 and E2 of HCV and shielding of important epitopes by hypervariable region 1 (HVR1) of E2 are believed to be major hindrances to developing universally protect...
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| Publicat a: | Hepatology |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5115964/ https://ncbi.nlm.nih.gov/pubmed/27351277 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.28705 |
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