Neutralization resistance of hepatitis C virus can be overcome by recombinant human monoclonal antibodies

Immunotherapy and vaccine development for hepatitis C virus (HCV) will depend on broadly reactive neutralizing antibodies. However, studies in infectious JFH1-based culture systems expressing patient derived Core-NS2 proteins have suggested neutralization resistance for specific HCV strains, in part...

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Detalhes bibliográficos
Publicado no:Hepatology
Main Authors: Pedersen, Jannie, Carlsen, Thomas H. R., Prentoe, Jannick, Ramirez, Santseharay, Jensen, Tanja B., Forns, Xavier, Alter, Harvey, Foung, Steven K. H., Law, Mansun, Gottwein, Judith, Weis, Nina, Bukh, Jens
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4415732/
https://ncbi.nlm.nih.gov/pubmed/23729237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.26524
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