Breadth of neutralization and synergy of clinically relevant human monoclonal antibodies against HCV genotypes 1a, 1b, 2a, 2b, 2c, and 3a

Human monoclonal antibodies (HMAbs) with neutralizing capabilities constitute potential immune-based treatments or prophylaxis against hepatitis C virus (HCV). However, lack of cell culture-derived HCV (HCVcc) harboring authentic envelope proteins (E1/E2) has hindered neutralization investigations a...

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Detalhes bibliográficos
Publicado no:Hepatology
Main Authors: Carlsen, Thomas H.R., Pedersen, Jannie, Prentoe, Jannick C., Giang, Erick, Keck, Zhen-Yong, Mikkelsen, Lotte S., Law, Mansun, Foung, Steven K. H., Bukh, Jens
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4415877/
https://ncbi.nlm.nih.gov/pubmed/25043937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.27298
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