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Corticosteroid insensitive alveolar macrophages from asthma patients; synergistic interaction with a p38 mitogen-activated protein kinase (MAPK) inhibitor
AIMS: Some asthma patients remain symptomatic despite using high doses of inhaled corticosteroids (ICS). We used alveolar macrophages to identify individual patients with insensitivity to corticosteroids and to evaluate the anti-inflammatory effects of a p38 mitogen-activated protein kinase (MAPK) i...
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Опубликовано в: : | Br J Clin Pharmacol |
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Главные авторы: | , , , , , |
Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
BlackWell Publishing Ltd
2015
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4415712/ https://ncbi.nlm.nih.gov/pubmed/25358442 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12536 |
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