Mechanisms of corticosteroid insensitivity in COPD alveolar macrophages exposed to NTHi

BACKGROUND: Non-typeable Haemophilus influenza (NTHi) infection is common in COPD. Corticosteroids can have limited therapeutic effects in COPD patients. NTHi causes corticosteroid insensitive cytokine production from COPD alveolar macrophages. We investigated the mechanisms by which NTHi causes cor...

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Gepubliceerd in:Respir Res
Hoofdauteurs: Khalaf, Rana M., Lea, Simon R., Metcalfe, Hannah J., Singh, Dave
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2017
Onderwerpen:
Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5395788/
https://ncbi.nlm.nih.gov/pubmed/28420398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-017-0539-4
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