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Mechanisms of corticosteroid insensitivity in COPD alveolar macrophages exposed to NTHi

BACKGROUND: Non-typeable Haemophilus influenza (NTHi) infection is common in COPD. Corticosteroids can have limited therapeutic effects in COPD patients. NTHi causes corticosteroid insensitive cytokine production from COPD alveolar macrophages. We investigated the mechanisms by which NTHi causes cor...

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Bibliografske podrobnosti
izdano v:Respir Res
Main Authors: Khalaf, Rana M., Lea, Simon R., Metcalfe, Hannah J., Singh, Dave
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5395788/
https://ncbi.nlm.nih.gov/pubmed/28420398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-017-0539-4
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