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TIGAR regulates DNA damage and repair through pentosephosphate pathway and Cdk5-ATM pathway
Previous study revealed that the protective effect of TIGAR in cell survival is mediated through the increase in PPP (pentose phosphate pathway) flux. However, it remains unexplored if TIGAR plays an important role in DNA damage and repair. This study investigated the role of TIGAR in DNA damage res...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4415581/ https://ncbi.nlm.nih.gov/pubmed/25928429 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09853 |
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