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ATM and CDK2 control chromatin remodeler CSB to inhibit RIF1 in DSB repair pathway choice
CSB, a member of the SWI2/SNF2 superfamily, is implicated in DNA double-strand break (DSB) repair. However, how it regulates this repair process is poorly understood. Here we uncover that CSB interacts via its newly identified winged helix domain with RIF1, an effector of 53BP1, and that this intera...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5715124/ https://ncbi.nlm.nih.gov/pubmed/29203878 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02114-x |
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