SHP2 regulates osteoclastogenesis by promoting preosteoclast fusion

Genes that regulate osteoclast (OC) development and function in both physiologic and disease conditions remain incompletely understood. Shp2 (the Src homology-2 domain containing protein tyrosine phosphatase 2), a ubiquitously expressed cytoplasmic protein tyrosine phosphatase, is implicated in regu...

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Detalles Bibliográficos
Publicado en:FASEB J
Autores principales: Zhou, Yi, Mohan, Aron, Moore, Douglas C., Lin, Liangjun, Zhou, Frank Li, Cao, Jay, Wu, Qian, Qin, Yi-Xian, Reginato, Anthony M., Ehrlich, Michael G., Yang, Wentian
Formato: Artigo
Lenguaje:Inglês
Publicado: Federation of American Societies for Experimental Biology 2015
Materias:
Life Sciences Forum
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4415019/
https://ncbi.nlm.nih.gov/pubmed/25593124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-260844
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