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CCL4 enhances preosteoclast migration and its receptor CCR5 downregulation by RANKL promotes osteoclastogenesis

Chemokine CCL4 (MIP-1β) is released from osteoblast cells to restore the homeostasis of hematopoietic stem cells during the activation of bone marrow. In this study, we investigated the function of CCL4 and its receptor CCR5 during osteoclastogenesis. CCL4 promoted the migration and viability of pre...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Lee, Dabin, Shin, Kyung-Ju, Kim, Dong Wook, Yoon, Kyung-Ae, Choi, Young-Jin, Lee, Bom Nae Rin, Cho, Je-Yoel
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5931580/
https://ncbi.nlm.nih.gov/pubmed/29717113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0562-5
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