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CCL4 enhances preosteoclast migration and its receptor CCR5 downregulation by RANKL promotes osteoclastogenesis

Chemokine CCL4 (MIP-1β) is released from osteoblast cells to restore the homeostasis of hematopoietic stem cells during the activation of bone marrow. In this study, we investigated the function of CCL4 and its receptor CCR5 during osteoclastogenesis. CCL4 promoted the migration and viability of pre...

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Библиографические подробности
Опубликовано в: :Cell Death Dis
Главные авторы: Lee, Dabin, Shin, Kyung-Ju, Kim, Dong Wook, Yoon, Kyung-Ae, Choi, Young-Jin, Lee, Bom Nae Rin, Cho, Je-Yoel
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5931580/
https://ncbi.nlm.nih.gov/pubmed/29717113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0562-5
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