Interaction of the Androgen Receptor, ETV1, and PTEN Pathways in Mouse Prostate Varies with Pathological Stage and Predicts Cancer Progression

To examine the impact of common somatic mutations in prostate cancer (PCa) on androgen receptor (AR) signaling, mouse models were designed to perturb sequentially the AR, ETV1, and PTEN pathways. Mice with “humanized” AR (hAR) alleles that modified AR transcriptional strength by varying polyglutamin...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Horm Cancer
Egile Nagusiak: Higgins, Jake, Brogley, Michele, Palanisamy, Nallasivam, Mehra, Rohit, Ittmann, Michael M., Li, Jun Z., Tomlins, Scott A., Robins, Diane M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Springer US 2015
Gaiak:
Original Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4414739/
https://ncbi.nlm.nih.gov/pubmed/25631336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12672-014-0215-9
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