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Differential modulation of the androgen receptor for prostate cancer therapy depends on the DNA response element

Androgen receptor (AR) action is a hallmark of prostate cancer (PCa) with androgen deprivation being standard therapy. Yet, resistance arises and aberrant AR signaling promotes disease. We sought compounds that inhibited genes driving cancer but not normal growth and hypothesized that genes with con...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Kregel, Steven, Bagamasbad, Pia, He, Shihan, LaPensee, Elizabeth, Raji, Yemi, Brogley, Michele, Chinnaiyan, Arul, Cieslik, Marcin, Robins, Diane M
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7229860/
https://ncbi.nlm.nih.gov/pubmed/32198885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa178
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