Androgen receptor uses relaxed response element stringency for selective chromatin binding and transcriptional regulation in vivo

The DNA-binding domains (DBDs) of class I steroid receptors—androgen, glucocorticoid, progesterone and mineralocorticoid receptors—recognize a similar cis-element, an inverted repeat of 5′-AGAACA-3′ with a 3-nt spacer. However, these receptors regulate transcription programs that are largely recepto...

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Autors principals: Sahu, Biswajyoti, Pihlajamaa, Päivi, Dubois, Vanessa, Kerkhofs, Stefanie, Claessens, Frank, Jänne, Olli A.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
Matèries:
Gene Regulation, Chromatin and Epigenetics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985627/
https://ncbi.nlm.nih.gov/pubmed/24459135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1401
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