SUMO ligase PIAS1 functions as a target gene selective androgen receptor coregulator on prostate cancer cell chromatin

Androgen receptor (AR) is a ligand-activated transcription factor that plays a central role in the development and growth of prostate carcinoma. PIAS1 is an AR- and SUMO-interacting protein and a putative transcriptional coregulator overexpressed in prostate cancer. To study the importance of PIAS1...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Toropainen, Sari, Malinen, Marjo, Kaikkonen, Sanna, Rytinki, Miia, Jääskeläinen, Tiina, Sahu, Biswajyoti, Jänne, Olli A., Palvimo, Jorma J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Gene regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4333416/
https://ncbi.nlm.nih.gov/pubmed/25552417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1375
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