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15-oxoeicosatetraenoic acid is a 15-hydroxyprostaglandin dehydrogenase-derived electrophilic mediator of inflammatory signaling pathways

Bioactive lipids govern cellular homeostasis and pathogenic inflammatory processes. Current dogma holds that bioactive lipids, such as prostaglandins and lipoxins, are inactivated by 15-hydroxyprostaglandin dehydrogenase (15PGDH). In contrast, the present results reveal that catabolic “inactivation”...

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Podrobná bibliografie
Vydáno v:Chem Biol Interact
Hlavní autoři: Snyder, Nathaniel W., Golin-Bisello, Franca, Gao, Yang, Blair, Ian A., Freeman, Bruce A., Wendell, Stacy Gelhaus
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4414684/
https://ncbi.nlm.nih.gov/pubmed/25450232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2014.10.029
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