15-Hydroxyprostaglandin Dehydrogenase Generation of Electrophilic Lipid Signaling Mediators from Hydroxy Ω-3 Fatty Acids

15-Hydroxyprostaglandin dehydrogenase (15PGDH) is the primary enzyme catalyzing the conversion of hydroxylated arachidonic acid species to their corresponding oxidized metabolites. The oxidation of hydroxylated fatty acids, such as the conversion of prostaglandin (PG) E(2) to 15-ketoPGE(2), by 15PGD...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Wendell, Stacy Gelhaus, Golin-Bisello, Franca, Wenzel, Sally, Sobol, Robert W., Holguin, Fernando, Freeman, Bruce A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Lipids
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4342494/
https://ncbi.nlm.nih.gov/pubmed/25586183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.635151
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