15-Hydroxyprostaglandin Dehydrogenase Is Down-regulated in Colorectal Cancer

Prostaglandin E(2) (PGE(2)) can stimulate tumor progression by modulating several proneoplastic pathways, including proliferation, angiogenesis, cell migration, invasion, and apoptosis. Although steady-state tissue levels of PGE(2) stem from relative rates of biosynthesis and breakdown, most reports...

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Hlavní autoři: Backlund, Michael G., Mann, Jason R., Holla, Vijaykumar R., Buchanan, F. Gregory, Tai, Hsin-Hsiung, Musiek, Erik S., Milne, Ginger L., Katkuri, Sharada, DuBois, Raymond N.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2004
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1847633/
https://ncbi.nlm.nih.gov/pubmed/15542609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M411221200
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