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Early pregnancy loss in 15-hydroxyprostaglandin dehydrogenase knockout (15-HPGD(−/−)) mice due to requirement for embryo 15-HPGD activity

Prostaglandins (PGs) have critical signaling functions in a variety of processes including the establishment and maintenance of pregnancy, and the initiation of labor. Most PGs are non-enzymatically degraded, however, the two PGs most prominently implicated in the termination of pregnancy, including...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Roizen, Jeffrey D., Asada, Minoru, Tong, Min, Tai, Hsin-Hsiung, Muglia, Louis J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6879597/
https://ncbi.nlm.nih.gov/pubmed/31772225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-54064-7
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