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15-oxoeicosatetraenoic acid is a 15-hydroxyprostaglandin dehydrogenase-derived electrophilic mediator of inflammatory signaling pathways

Bioactive lipids govern cellular homeostasis and pathogenic inflammatory processes. Current dogma holds that bioactive lipids, such as prostaglandins and lipoxins, are inactivated by 15-hydroxyprostaglandin dehydrogenase (15PGDH). In contrast, the present results reveal that catabolic “inactivation”...

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Detalhes bibliográficos
Publicado no:Chem Biol Interact
Main Authors: Snyder, Nathaniel W., Golin-Bisello, Franca, Gao, Yang, Blair, Ian A., Freeman, Bruce A., Wendell, Stacy Gelhaus
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4414684/
https://ncbi.nlm.nih.gov/pubmed/25450232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2014.10.029
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