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Development of a high-throughput in vitro assay to identify selective inhibitors for human ALDH1A1
The human aldehyde dehydrogenase (ALDH) superfamily consists of at least 19 enzymes that metabolize endogenous and exogenous aldehydes. Currently, there are no commercially available inhibitors that target ALDH1A1 but have little to no effect on the structurally and functionally similar ALDH2. Here...
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| Publicado no: | Chem Biol Interact |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4414680/ https://ncbi.nlm.nih.gov/pubmed/25450233 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2014.10.028 |
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