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Dexamethasone Treatment of Newborn Rats Decreases Cardiomyocyte Endowment in the Developing Heart through Epigenetic Modifications

The potential adverse effect of synthetic glucocorticoid, dexamethasone therapy on the developing heart remains unknown. The present study investigated the effects of dexamethasone on cardiomyocyte proliferation and binucleation in the developing heart of newborn rats and evaluated DNA methylation a...

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Podrobná bibliografie
Vydáno v:PLoS One
Hlavní autoři: Gay, Maresha S., Li, Yong, Xiong, Fuxia, Lin, Thant, Zhang, Lubo
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4414482/
https://ncbi.nlm.nih.gov/pubmed/25923220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0125033
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